Application of Calcium D-Glucarate
Oral supplementation of D-saccharic acid calcium salt tetrahydrate has been shown to inhibit beta-glucuronidase, an enzyme produced by colonic microflora and involved in Phase II liver detoxification. Other potential clinical applications of oral calcium saccharate tetrahydrate include the regulation of estrogen metabolism and as a lipid-lowering agent.
Pharmacology
Oral D-Glucaric acid calcium salt supplementation has been shown to prevent the body from reabsorbing and recycling hormones and harmful environmental toxins. It does this by supporting increased glucuronidation (phase 2 liver detoxification) and inhibiting beta-glucuronidase, which facilitates the secretion of potentially harmful compounds and hormones.
D-Saccharic acid calcium salt is regarded as a key nutrient for optimizing hormonal health. This is because it supports liver metabolism and may inhibit beta-glucuronidase, an enzyme that is associated with higher rates of hormone-related cancers.
Health benefits of Calcium D-Glucarate include:
1. Supports liver detoxification
2. May reduce estrogen levels
3. Potentially inhibits some types of cancer
4. Helps maintain already healthy cholesterol levels
Parameters of Calcium D-Glucarate
| Items | Specification |
|---|---|
| Name | Calcium D-Saccharate Tetrahydrate |
| Other Name | D-saccharic acid calcium salt tetrahydrate; Calcium Saccharate Tetrahydrate; Calcium Saccharate; D-Glucaric acid calcium salt; D-Saccharic acid calcium salt |
| Brand | Natural Micron Pharm Tech |
| Cas Number | 5793-89-5 |
| EINECS Number | 611-592-0 |
| Appearance | White solid powder |
| Molecular Formula | C6H14CaO9 |
| Structure Formula | ![]() |
| Molecular Weight | 270.25 |
| Purity(HPLC) | 98.5%-102.0% |
| Melting Point | >185oC (dec.) |
| Water Solubility | Soluble in water(0.43g/L). |
| Stability | Hygroscopic |
| Place of Origin | China |
| Shelf Life | 2 Years |
| Package | Aluminum Foil Bag/Drum |
| Storage | Store in dry and ventilated place with the room temperature. Preserved in original tight-closed containers. Keep away from light and heating. |







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